# Knowledge Check A self-scored quiz covering every lesson on Nodule Navigator. Each run draws **ten questions at random** from a bank of **38**, so the quiz can be retaken without repeating the same set. ## How it works - Ten questions per run, drawn at random from the full bank and shuffled. - Each question is either true/false or multiple choice with four options. - Answering locks in the choice and immediately reveals whether it was correct, an explanation of why, and the source citation the question is drawn from. - A score and a tier are shown at the end: 8 or more out of 10 is "Excellent", 6 to 7 is "Nice work", below 6 is "Keep Exploring". - Nothing is recorded. Scores are not stored, transmitted, or logged. ## The question bank 38 questions — 20 multiple choice, 18 true/false — distributed across the lessons as follows: | Lesson | Questions | |---|---| | Nodule Types | 8 | | Lung Cancer Facts | 6 | | Risk Factors & Symptoms | 8 | | What Is a Biomarker? | 6 | | Biomarker Testing | 6 | | Mixed | 4 | ## What each lesson is tested on Question text and answers are deliberately not reproduced. Roughly half the bank is true/false, and printing those statements would hand over the answers. The topics are: ### Nodule Types (8 questions) - The size definition that separates a nodule from a mass. - The Fleischner Society size thresholds that trigger follow-up imaging. - How solid, part-solid, and ground-glass density appear on CT and how their risk differs. - Which margin morphologies raise malignancy suspicion. - How nodule location factors into risk. - What an incidental finding does and does not warrant. ### Lung Cancer Facts (6 questions) - Lung cancer mortality relative to other cancers in the United States. - The distribution of stage at diagnosis. - How five-year survival changes with stage. - The screening modality recommended for high-risk adults. - The most common histologic type. - Incidence and mortality trends over the past two decades. ### Risk Factors & Symptoms (8 questions) - The largest single risk factor, and how much it raises risk. - The definition and arithmetic of a pack-year. - Causes of lung cancer in never-smokers, including radon. - How large a share of cases occur in people who never smoked. - The B.R.E.A.T.H.E. symptom framework and what each letter stands for. - How long a symptom should persist before it warrants attention. - The three USPSTF criteria for LDCT screening eligibility. ### What Is a Biomarker? (6 questions) - What a biomarker is, and what counts as one. - Why two identical diagnoses can behave differently. - What a molecular fingerprint is and where it is written. - Tissue biopsy versus liquid biopsy. - What precision medicine means in practice. ### Biomarker Testing (6 questions) - What a driver mutation is and why it is targetable. - The common actionable mutations in NSCLC and their approximate frequencies. - What next-generation sequencing does and what a single panel covers. - How targeted therapy response rates compare with unmatched chemotherapy. - What a positive and a negative result each mean for treatment options. - What NCCN recommends about molecular profiling at diagnosis. ### Mixed (4 questions) - Questions that span more than one lesson, connecting imaging findings, risk factors, and molecular testing. ## Sources Every question carries its own citation, shown after answering. The bank draws on the Fleischner Society 2017 guidelines, Lung-RADS v2022, USPSTF 2021 screening recommendations, the National Lung Screening Trial, NCCN guidelines, SEER and American Cancer Society statistics, and cited peer-reviewed literature. Full citations are on the [references page](https://nodule.app/references). ## Related - [Education hub](https://nodule.app/education) — the lessons the questions are drawn from. - [Take the quiz](https://nodule.app/quiz) — the interactive version. --- *Educational use only · Not a medical device.* This document mirrors the page at .